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37360 painful tail flick
Measure the pain threshold of the tail of mice and rats subjected to infrared thermal stimulation
Product details
- Product Name: 37360 Pain Tail Shake
- Order number: tlyon000400
- Brand Name: Ugo Italy
If you find that the product information is inaccurate, please feel free to correct it; For inquiries about related categories and brand products, please contact us37360- Pain induced tail flick
characteristic
advantage
The instrument automatically records experimental data
High precision, avoiding errors caused by human factors
Includes USB flash drive and software
Can work independently or connect to a computer for use
There are no protruding or obstructed objects on the surface of the instrument workbench
Easy to operate, good repeatability of experiments
Specifications:
Command:
Soft keys and foot pedals
Connect computer:
DELTA 9-pin connector, USB connection
Data reading:
liquid crystal display
Power Supply:
universal mains 85-264 VAC, 50-60Hz
Printing:
Micro thermal printer (to be purchased separately)
Working temperature:
15° - 30° C
Start:
Infrared switch
Sound level:
< 70 dB
Infrared intensity:
Adjustable between levels 10-99
Infrared light source bulb;
Halogen "Bellaphot", Mod. 64607 OSRAM, 8V-50W
Reaction time:
LCD display with a resolution of 0.1s
Calibration:
Infrared thermal radiometer (to be purchased separately)
deadline:
Pre set, between 15-60 seconds
enclosure:
37360-325:
Mouse restraint device, 25 mm I.D
37360-330:
E-HR 002:
Mouse restraint device, 30 mm I.D
Replace the light bulb
37300
Infrared thermal radiometer
57145
Micro printer
references
method
- F.E. D’Amour & D.L. Smith: "A Method for Determining Loss of Pain Sensation." J. Pharmacol. Exp. Therap. 72: 74-79, 1941.
Tail flick experiment involving UB- T.O. Lilius et alia: "The Mineralocorticoid Receptor Antagonist Spironolactone Enhances Morphine Antinociception” Eur. J. of Pain online view, 2013
- J.W. Little et alia: “Spinal Mitochondrial-Derived Peroxynitrite Enhances Neuroimmune Activation During Morphine Hyperalgesia and Antinociceptive Tolerance” Pain 154 (7): 978-986, 2013
- P.J. McLaughlin et alia: “Behavioral Effects of the Novel Potent Cannabinoid CB1 Agonist AM 4054”Pharmacology Biochemistry and Behavior 109: 16-22, 2013
- T.A. Kosten et alia: “A Morphine Conjugate Vaccine Attenuates the Behavioral Effects of Morphine in Rats” Progr. in Neuro-Psychopharmacol. and Biol. Psychiatry 45: 223–229, 2013
- T.C. Chen et alia: “Spontaneous inflammatory Pain Model From a Mouse Line With N-ethyl-N-nitrosourea Mutagenesis” J. Biomed. Science 19 (55): 2–15, 2012
- J. Walsh et alia: “Disruption of Thermal Nociceptive Behaviour in Mice Mutant for the Schizophrenia-Associated Genes NRG1, COMT and DISC1” Brain Res. 1348: 114-119, 2012
- K. Guillemyn et alia: “In vivo Antinociception of Potent mu Opioid Agonist Tetrapeptide Analogues and Comparison with a Compact Opioid Agonist-neurokin 1 Receptor Antagonist Chimera” Molecular Brain5 (4): 2-11, 2012
- A.J. Morrison et alia: “Design, Synthesis, and Structure–Activity Relationships of indole-3-heterocycles as Agonists of the CB1 Receptor” Bioorganic & Medicinal Chemistry Letters 21: 506-509, 2011
- M. Spetea et alia: “In vitro and in vivo Pharmacological Profile of the 5-benzyl Analogue of 14-methoxymetopon, a Novel μ Opioid Analgesic with Reduced Propensity to Alter Motor Function” Eur. J. Pharmac. Sciences 41: 125-135, 2010
- C.A. Boehm et alia: “Midazolam Enhances the Analgesic Properties of Dexmedetomidine in the Rat”Vet. Anaesthesia and Analgesia 37 (6): 550-556, 2010
- M.A. Philips et alia: “Myg1-Deficient Mice Display Alterations in Stress-Induced Responses and Reduction of Sex-Dependent Behavioural Differences” Behav. Brain Res. 207: 182-195, 2010
- C. Dawson et alia: “ Dexmedetomidine Enhances Analgesic Action of Nitrous Oxide” Anesthesiology 100 (4): 894−904, 2004
- P. Tolu et alia: “ Effects of Long-Term Acetyl-L-carnitine Administation in Rats: I. Increased Dopamine Output in Mesocorticolimbic Areas and Protection Toward Acute Stress Exposure” Neuropsychopharmacol. 27 (3): 410-420, 2002
- R. Nadeson et alia: “ Potentiation by Ketamine of Fentanyl Antinociception. I. An Experimental Study in Rats Showing that Ketamine Administered by Non-Spinal Routes Targets Spinal Cord Antinociceptive Systems” Br. J. Anaesthesia 88 (5): 685−691, 2002- L. Jasmin et alia: “ The NK1 Receptor mediates Both the Hyperalgesia and the Resistance to Morphine in Mice Lacking Noradrenaline” PNAS 99 (2): 1029−1034, 2002- G.L. Fraser et alia: “ Antihyperalgesic Effects of Opioid Agonists in a Rat Model of Chronic Inflammation” Br. J. Pharmacol. 129: 1668−1672, 2000- M. Xu et alia: “ Effects of Radolmidine, a Novel α2- Adrenergic Agonist Compared with Dexmedetomidine in Different Pain Models in the Rat” Anesthesiology 93 (2): 473−481, 2000- A. Kö ster et alia: “Targeted Disruption of the Orphanin Fq/Nociceptin Gene Increases Stress Susceptibility and Impairs Stress Adaptation In Mice” Neurobiology 96 (18): 10444-10449, 1999- I. Sora et alia: “Opiate Receptor Knockout Mice Define µ Receptor Roles in Endogenous Nociceptive Responses and Morphine-Induced Analgesia” Neurobiology 94: 1544-1549, 1997- C.T. Dourish et alia: "The Selective CCK-B Receptor Antagonist L-365,260 Enhances Morphine Analgesia and Prevents Morphine Tolerance in the Rat" Europ. J. Pharmacol. 176: 35-44, 1990- P.W. Nance & J. Sawinok: "Substance P-Induced Long-Term Blockade of Spinal Adrenergic Analgesia: Reversal by Morphine and Naloxone" J. Pharmacol. Exp. Therap. Vol. 240, No. 3: 972-977, 1987
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